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Hypercontractile Cardiac Phenotype in Mice with Migraine-Associated Mutation in the Na(+),K(+)-ATPase α(2)-Isoform

Two α-isoforms of the Na(+),K(+)-ATPase (α(1) and α(2)) are expressed in the cardiovascular system, and it is unclear which isoform is the preferential regulator of contractility. Mice heterozygous for the familial hemiplegic migraine type 2 (FHM2) associated mutation in the α(2)-isoform (G301R; α(2...

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Detalles Bibliográficos
Autores principales: Rajanathan, Rajkumar, Riera, Clàudia Vilaseca i, Pedersen, Tina Myhre, Staehr, Christian, Bouzinova, Elena V., Nyengaard, Jens Randel, Thomsen, Morten B., Bøtker, Hans Erik, Matchkov, Vladimir V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136638/
https://www.ncbi.nlm.nih.gov/pubmed/37190017
http://dx.doi.org/10.3390/cells12081108

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