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SRSF5 Regulates the Expression of BQ323636.1 to Modulate Tamoxifen Resistance in ER-Positive Breast Cancer

SIMPLE SUMMARY: Overexpression of BQ can confer tamoxifen resistance in ER +ve breast cancer. BQ is a variant of NCOR2 spliced through the exclusion of exon 11. SRSF5 is found to be involved in regulating the splicing of NCOR2. A low expression of SRSF5 enhances the chance of excluding exon 11 from...

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Detalles Bibliográficos
Autores principales:	Tsoi, Ho, Fung, Nicholas Nok-Ching, Man, Ellen P. S., Leung, Man-Hong, You, Chan-Ping, Chan, Wing-Lok, Chan, Sum-Yin, Khoo, Ui-Soon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136643/ https://www.ncbi.nlm.nih.gov/pubmed/37190199 http://dx.doi.org/10.3390/cancers15082271

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