Correlation of Electrophysiological and Fluorescence-Based Measurements of Modulator Efficacy in Nasal Epithelial Cultures Derived from People with Cystic Fibrosis

It has been suggested that in vitro studies of the rescue effect of CFTR modulator drugs in nasal epithelial cultures derived from people with cystic fibrosis have the potential to predict clinical responses to the same drugs. Hence, there is an interest in evaluating different methods for measuring...

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Detalles Bibliográficos
Autores principales: Gunawardena, Tarini N. A., Bozóky, Zoltán, Bartlett, Claire, Ouyang, Hong, Eckford, Paul D. W., Moraes, Theo J., Ratjen, Felix, Gonska, Tanja, Bear, Christine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136647/
https://www.ncbi.nlm.nih.gov/pubmed/37190083
http://dx.doi.org/10.3390/cells12081174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136647/
https://www.ncbi.nlm.nih.gov/pubmed/37190083
http://dx.doi.org/10.3390/cells12081174

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