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Correlation of Electrophysiological and Fluorescence-Based Measurements of Modulator Efficacy in Nasal Epithelial Cultures Derived from People with Cystic Fibrosis
It has been suggested that in vitro studies of the rescue effect of CFTR modulator drugs in nasal epithelial cultures derived from people with cystic fibrosis have the potential to predict clinical responses to the same drugs. Hence, there is an interest in evaluating different methods for measuring...
Autores principales: | Gunawardena, Tarini N. A., Bozóky, Zoltán, Bartlett, Claire, Ouyang, Hong, Eckford, Paul D. W., Moraes, Theo J., Ratjen, Felix, Gonska, Tanja, Bear, Christine E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136647/ https://www.ncbi.nlm.nih.gov/pubmed/37190083 http://dx.doi.org/10.3390/cells12081174 |
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