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Sleep Apnea and Substance Use Disorders Associated with Co-Occurrence of Anxiety Disorder and Depression among U.S. Adults: Findings from the NSDUH 2008–2014

Few studies have focused on sleep apnea and substance use disorders with co-occurrence of anxiety disorder and depression. This study included a total of 270,227 adults, 9268 with co-occurrence of anxiety disorder and depression in the past year, from the combined 2008–2014 National Survey on Drug U...

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Autores principales: Xu, Chun, Acevedo, Priscila, Wang, Liang, Wang, Nianyang, Ozuna, Kaysie, Shafique, Saima, Karithara, Annu, Padilla, Victoria, Mao, Chunxiang, Xie, Xin, Wang, Kesheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136804/
https://www.ncbi.nlm.nih.gov/pubmed/37190626
http://dx.doi.org/10.3390/brainsci13040661
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author Xu, Chun
Acevedo, Priscila
Wang, Liang
Wang, Nianyang
Ozuna, Kaysie
Shafique, Saima
Karithara, Annu
Padilla, Victoria
Mao, Chunxiang
Xie, Xin
Wang, Kesheng
author_facet Xu, Chun
Acevedo, Priscila
Wang, Liang
Wang, Nianyang
Ozuna, Kaysie
Shafique, Saima
Karithara, Annu
Padilla, Victoria
Mao, Chunxiang
Xie, Xin
Wang, Kesheng
author_sort Xu, Chun
collection PubMed
description Few studies have focused on sleep apnea and substance use disorders with co-occurrence of anxiety disorder and depression. This study included a total of 270,227 adults, 9268 with co-occurrence of anxiety disorder and depression in the past year, from the combined 2008–2014 National Survey on Drug Use and Health (NSDUH) data, which are the latest datasets with measures of anxiety disorder and sleep apnea. Weighted multinomial logistic regression analyses were used to estimate the associations between anxiety disorder and depression and their co-occurrence. Comorbidity was highly prevalent: 40.4% of those with depression also met the criteria for anxiety disorder, whereas 51.8% of those with anxiety disorder also met the criteria for depression. The prevalences of anxiety only and co-occurrence increased from 2008 to 2014. The prevalences of anxiety disorder only, depression only, and co-occurrence of anxiety disorder and depression in individuals with sleep apnea were 4.4%, 12.9%, and 12.2%, respectively, and the prevalences in substance use disorders were 6.4%, 9.4%, and 10.7%, respectively. The results showed that sleep apnea, substance use disorders, and nicotine dependence were significantly associated with increased odds of anxiety disorder, depression, and co-occurrence (all p values < 0.0001). Furthermore, several chronic diseases (asthma, bronchitis, hypertension, and heart disease) were associated with the co-occurrence of anxiety disorder and depression. These findings suggest clinicians and other healthcare providers consider screening for depression and anxiety with sleep apnea and substance use disorders for improved therapeutic outcomes.
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spelling pubmed-101368042023-04-28 Sleep Apnea and Substance Use Disorders Associated with Co-Occurrence of Anxiety Disorder and Depression among U.S. Adults: Findings from the NSDUH 2008–2014 Xu, Chun Acevedo, Priscila Wang, Liang Wang, Nianyang Ozuna, Kaysie Shafique, Saima Karithara, Annu Padilla, Victoria Mao, Chunxiang Xie, Xin Wang, Kesheng Brain Sci Article Few studies have focused on sleep apnea and substance use disorders with co-occurrence of anxiety disorder and depression. This study included a total of 270,227 adults, 9268 with co-occurrence of anxiety disorder and depression in the past year, from the combined 2008–2014 National Survey on Drug Use and Health (NSDUH) data, which are the latest datasets with measures of anxiety disorder and sleep apnea. Weighted multinomial logistic regression analyses were used to estimate the associations between anxiety disorder and depression and their co-occurrence. Comorbidity was highly prevalent: 40.4% of those with depression also met the criteria for anxiety disorder, whereas 51.8% of those with anxiety disorder also met the criteria for depression. The prevalences of anxiety only and co-occurrence increased from 2008 to 2014. The prevalences of anxiety disorder only, depression only, and co-occurrence of anxiety disorder and depression in individuals with sleep apnea were 4.4%, 12.9%, and 12.2%, respectively, and the prevalences in substance use disorders were 6.4%, 9.4%, and 10.7%, respectively. The results showed that sleep apnea, substance use disorders, and nicotine dependence were significantly associated with increased odds of anxiety disorder, depression, and co-occurrence (all p values < 0.0001). Furthermore, several chronic diseases (asthma, bronchitis, hypertension, and heart disease) were associated with the co-occurrence of anxiety disorder and depression. These findings suggest clinicians and other healthcare providers consider screening for depression and anxiety with sleep apnea and substance use disorders for improved therapeutic outcomes. MDPI 2023-04-14 /pmc/articles/PMC10136804/ /pubmed/37190626 http://dx.doi.org/10.3390/brainsci13040661 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Xu, Chun
Acevedo, Priscila
Wang, Liang
Wang, Nianyang
Ozuna, Kaysie
Shafique, Saima
Karithara, Annu
Padilla, Victoria
Mao, Chunxiang
Xie, Xin
Wang, Kesheng
Sleep Apnea and Substance Use Disorders Associated with Co-Occurrence of Anxiety Disorder and Depression among U.S. Adults: Findings from the NSDUH 2008–2014
title Sleep Apnea and Substance Use Disorders Associated with Co-Occurrence of Anxiety Disorder and Depression among U.S. Adults: Findings from the NSDUH 2008–2014
title_full Sleep Apnea and Substance Use Disorders Associated with Co-Occurrence of Anxiety Disorder and Depression among U.S. Adults: Findings from the NSDUH 2008–2014
title_fullStr Sleep Apnea and Substance Use Disorders Associated with Co-Occurrence of Anxiety Disorder and Depression among U.S. Adults: Findings from the NSDUH 2008–2014
title_full_unstemmed Sleep Apnea and Substance Use Disorders Associated with Co-Occurrence of Anxiety Disorder and Depression among U.S. Adults: Findings from the NSDUH 2008–2014
title_short Sleep Apnea and Substance Use Disorders Associated with Co-Occurrence of Anxiety Disorder and Depression among U.S. Adults: Findings from the NSDUH 2008–2014
title_sort sleep apnea and substance use disorders associated with co-occurrence of anxiety disorder and depression among u.s. adults: findings from the nsduh 2008–2014
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136804/
https://www.ncbi.nlm.nih.gov/pubmed/37190626
http://dx.doi.org/10.3390/brainsci13040661
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