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Integrated Metabolomic and Transcriptomic Analysis of Modified Nucleosides for Biomarker Discovery in Clear Cell Renal Cell Carcinoma

Clear cell renal cell carcinoma (ccRCC) accounts for ~75% of kidney cancers. The biallelic inactivation of the von Hippel–Lindau tumor suppressor gene (VHL) is the truncal driver mutation of most cases of ccRCC. Cancer cells are metabolically reprogrammed and excrete modified nucleosides in larger a...

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Detalles Bibliográficos
Autores principales:	Mohl, Daniel A., Lagies, Simon, Zodel, Kyra, Zumkeller, Matthias, Peighambari, Asin, Ganner, Athina, Plattner, Dietmar A., Neumann-Haefelin, Elke, Adlesic, Mojca, Frew, Ian J., Kammerer, Bernd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136813/ https://www.ncbi.nlm.nih.gov/pubmed/37190010 http://dx.doi.org/10.3390/cells12081102

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