VISTA Ligation Reduces Antitumor T-Cell Activity in Pancreatic Cancer

SIMPLE SUMMARY: The V-domain Ig suppressor of T-cell activation (VISTA) suppresses T-cell effector function, and has been investigated as an alternative immunotherapeutic target in several cancers. In this study, we found increased VISTA expression in pancreatic tumor cells to be associated with dec...

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Detalles Bibliográficos
Autores principales: Digomann, David, Strack, Johannes, Heiduk, Max, Plesca, Ioana, Rupp, Luise, Reiche, Charlotte, Nicolaus, Simone, Beer, Carolin, Sommer, Ulrich, Schmitz, Marc, Distler, Marius, Weitz, Jürgen, Seifert, Adrian M., Seifert, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136841/
https://www.ncbi.nlm.nih.gov/pubmed/37190254
http://dx.doi.org/10.3390/cancers15082326

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