Fyn Phosphorylates Transglutaminase 2 (Tgm2) and Modulates Autophagy and p53 Expression in the Development of Diabetic Kidney Disease

Autophagy is involved in the development of diabetic kidney disease (DKD), the leading cause of end-stage renal disease. The Fyn tyrosine kinase (Fyn) suppresses autophagy in the muscle. However, its role in kidney autophagic processes is unclear. Here, we examined the role of Fyn kinase in autophag...

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Detalles Bibliográficos
Autores principales: Uehara, Ryota, Yamada, Eijiro, Okada, Shuichi, Bastie, Claire C., Maeshima, Akito, Ikeuchi, Hidekazu, Horiguchi, Kazuhiko, Yamada, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136856/
https://www.ncbi.nlm.nih.gov/pubmed/37190106
http://dx.doi.org/10.3390/cells12081197

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