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Pharmacological Modulation of the MIP-1 Family and Their Receptors Reduces Neuropathic Pain Symptoms and Influences Morphine Analgesia: Evidence from a Mouse Model

Neuropathic pain pathophysiology is not fully understood, but it was recently shown that MIP-1 family members (CCL3, CCL4, and CCL9) have strong pronociceptive properties. Our goal was to examine how pharmacological modulation of these chemokines and their receptors (CCR1 and CCR5) influence hyperse...

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Detalles Bibliográficos
Autores principales: Ciechanowska, Agata, Pawlik, Katarzyna, Ciapała, Katarzyna, Mika, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136865/
https://www.ncbi.nlm.nih.gov/pubmed/37190544
http://dx.doi.org/10.3390/brainsci13040579