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AKR1B1 Represses Glioma Cell Proliferation through p38 MAPK-Mediated Bcl-2/BAX/Caspase-3 Apoptotic Signaling Pathways

This study aimed to investigate the regulatory role of Aldo-keto reductase family 1 member B1 (AKR1B1) in glioma cell proliferation through p38 MAPK activation to control Bcl-2/BAX/caspase-3 apoptosis signaling. AKR1B1 expression was quantified in normal human astrocytes, glioblastoma multiforme (GB...

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Detalles Bibliográficos
Autores principales: Huang, Yu-Kai, Chang, Kun-Che, Li, Chia-Yang, Lieu, Ann-Shung, Lin, Chih-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136867/
https://www.ncbi.nlm.nih.gov/pubmed/37185746
http://dx.doi.org/10.3390/cimb45040222

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