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Infliximab Inhibits Colitis Associated Cancer in Model Mice by Downregulating Genes Associated with Mast Cells and Decreasing Their Accumulation

Inflammatory bowel diseases (IBDs), such as Crohn’s disease or ulcerative colitis, can be treated with anti TNF-alpha (TNF-α) antibodies (Abs), but they also put patients with IBDs at risk of cancer. We aimed to determine whether the anti TNF-α Ab induces colon cancer development in vitro and in viv...

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Detalles Bibliográficos
Autores principales:	Wang, Dan-Yang, Ohnuma, Shinobu, Suzuki, Hideyuki, Ishida, Masaharu, Ishii, Kentaro, Hirosawa, Takashi, Hirashima, Tomoaki, Murakami, Megumi, Kobayashi, Minoru, Kudoh, Katsuyoshi, Haneda, Sho, Musha, Hiroaki, Naitoh, Takeshi, Unno, Michiaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136890/ https://www.ncbi.nlm.nih.gov/pubmed/37185713 http://dx.doi.org/10.3390/cimb45040189

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