STAT3 Inhibition Attenuates MYC Expression by Modulating Co-Activator Recruitment and Suppresses Medulloblastoma Tumor Growth by Augmenting Cisplatin Efficacy In Vivo

SIMPLE SUMMARY: Medulloblastoma (MB) is a malignant brain tumor of childhood that occurs in the cerebellum and accounts for 20–25% of all pediatric central nervous system tumors. Despite improvement in overall survival rate, it still lacks an effective targeted treatment strategy. Here, we delineate...

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Detalles Bibliográficos
Autores principales: Rohrer, Kyle A., Song, Heyu, Akbar, Anum, Chen, Yingling, Pramanik, Suravi, Wilder, Phillip J., McIntyre, Erin M., Chaturvedi, Nagendra K., Bhakat, Kishor K., Rizzino, Angie, Coulter, Don W., Ray, Sutapa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136921/
https://www.ncbi.nlm.nih.gov/pubmed/37190167
http://dx.doi.org/10.3390/cancers15082239

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