A New Wave of Targeting ‘Undruggable’ Wnt Signaling for Cancer Therapy: Challenges and Opportunities

Aberrant Wnt signaling activation is frequently observed in many cancers. The mutation acquisition of Wnt signaling leads to tumorigenesis, whereas the inhibition of Wnt signaling robustly suppresses tumor development in various in vivo models. Based on the excellent preclinical effect of targeting...

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Detalles Bibliográficos
Autores principales: Park, Woo-Jung, Kim, Moon Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136927/
https://www.ncbi.nlm.nih.gov/pubmed/37190019
http://dx.doi.org/10.3390/cells12081110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136927/
https://www.ncbi.nlm.nih.gov/pubmed/37190019
http://dx.doi.org/10.3390/cells12081110

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