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Effect of Nigella sativa on Selected Gastrointestinal Diseases

Nigella sativa L. (family Ranunculaceae), also known as black cumin, has been used in cuisine around the world for many years. Due to its health-promoting properties, it can be used not only in the food industry but also in medicine. The main bioactive compound contained in the black cumin extract i...

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Autores principales: Jarmakiewicz-Czaja, Sara, Zielińska, Magdalena, Helma, Kacper, Sokal, Aneta, Filip, Rafał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136991/
https://www.ncbi.nlm.nih.gov/pubmed/37185722
http://dx.doi.org/10.3390/cimb45040198
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author Jarmakiewicz-Czaja, Sara
Zielińska, Magdalena
Helma, Kacper
Sokal, Aneta
Filip, Rafał
author_facet Jarmakiewicz-Czaja, Sara
Zielińska, Magdalena
Helma, Kacper
Sokal, Aneta
Filip, Rafał
author_sort Jarmakiewicz-Czaja, Sara
collection PubMed
description Nigella sativa L. (family Ranunculaceae), also known as black cumin, has been used in cuisine around the world for many years. Due to its health-promoting properties, it can be used not only in the food industry but also in medicine. The main bioactive compound contained in the black cumin extract is thymoquinone (TQ), which has a special therapeutic role. The results of research in recent years confirmed its hypoglycemic, hypolipemic, and hepatoprotective effects, among others. In addition, the results of laboratory tests also indicate its immunomodulatory and anticancer effects, although there is still a lack of data on the mechanisms of how they are involved in the fight against cancer. Including this plant material in one’s diet can be both an element of prophylaxis and therapy supporting the treatment process, including pharmacological treatment. However, attention should be paid to its potential interactions with drugs used in the treatment of chronic diseases.
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spelling pubmed-101369912023-04-28 Effect of Nigella sativa on Selected Gastrointestinal Diseases Jarmakiewicz-Czaja, Sara Zielińska, Magdalena Helma, Kacper Sokal, Aneta Filip, Rafał Curr Issues Mol Biol Review Nigella sativa L. (family Ranunculaceae), also known as black cumin, has been used in cuisine around the world for many years. Due to its health-promoting properties, it can be used not only in the food industry but also in medicine. The main bioactive compound contained in the black cumin extract is thymoquinone (TQ), which has a special therapeutic role. The results of research in recent years confirmed its hypoglycemic, hypolipemic, and hepatoprotective effects, among others. In addition, the results of laboratory tests also indicate its immunomodulatory and anticancer effects, although there is still a lack of data on the mechanisms of how they are involved in the fight against cancer. Including this plant material in one’s diet can be both an element of prophylaxis and therapy supporting the treatment process, including pharmacological treatment. However, attention should be paid to its potential interactions with drugs used in the treatment of chronic diseases. MDPI 2023-04-03 /pmc/articles/PMC10136991/ /pubmed/37185722 http://dx.doi.org/10.3390/cimb45040198 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Jarmakiewicz-Czaja, Sara
Zielińska, Magdalena
Helma, Kacper
Sokal, Aneta
Filip, Rafał
Effect of Nigella sativa on Selected Gastrointestinal Diseases
title Effect of Nigella sativa on Selected Gastrointestinal Diseases
title_full Effect of Nigella sativa on Selected Gastrointestinal Diseases
title_fullStr Effect of Nigella sativa on Selected Gastrointestinal Diseases
title_full_unstemmed Effect of Nigella sativa on Selected Gastrointestinal Diseases
title_short Effect of Nigella sativa on Selected Gastrointestinal Diseases
title_sort effect of nigella sativa on selected gastrointestinal diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136991/
https://www.ncbi.nlm.nih.gov/pubmed/37185722
http://dx.doi.org/10.3390/cimb45040198
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