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Therapy of Patients with Cardiac Malposition

Positional abnormalities per se do not require treatment, but in their place, the accompanying pulmonary pathology in dextroposition patients and pathophysiologic hemodynamic abnormalities resulting from multiple defects in patients with cardiac malposition should be the focus of treatment. At the t...

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Detalles Bibliográficos
Autor principal: Rao, P. Syamasundar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137016/
https://www.ncbi.nlm.nih.gov/pubmed/37189988
http://dx.doi.org/10.3390/children10040739
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author Rao, P. Syamasundar
author_facet Rao, P. Syamasundar
author_sort Rao, P. Syamasundar
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description Positional abnormalities per se do not require treatment, but in their place, the accompanying pulmonary pathology in dextroposition patients and pathophysiologic hemodynamic abnormalities resulting from multiple defects in patients with cardiac malposition should be the focus of treatment. At the time of the first presentation, treating the pathophysiologic aberrations caused by the defect complex, whether it is by improving the pulmonary blood flow or restricting it, is the first step. Some patients with simpler or single defects are amenable to surgical or transcatheter therapy and should be treated accordingly. Other associated defects should also be treated appropriately. Biventricular or univentricular repair dependent on the patient’s cardiac structure should be planned. Complications in-between Fontan stages and after conclusion of Fontan surgery may occur and should be promptly diagnosed and addressed accordingly. Several other cardiac abnormalities unrelated to the initially identified heart defects may manifest in adulthood, and they should also be treated.
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spelling pubmed-101370162023-04-28 Therapy of Patients with Cardiac Malposition Rao, P. Syamasundar Children (Basel) Review Positional abnormalities per se do not require treatment, but in their place, the accompanying pulmonary pathology in dextroposition patients and pathophysiologic hemodynamic abnormalities resulting from multiple defects in patients with cardiac malposition should be the focus of treatment. At the time of the first presentation, treating the pathophysiologic aberrations caused by the defect complex, whether it is by improving the pulmonary blood flow or restricting it, is the first step. Some patients with simpler or single defects are amenable to surgical or transcatheter therapy and should be treated accordingly. Other associated defects should also be treated appropriately. Biventricular or univentricular repair dependent on the patient’s cardiac structure should be planned. Complications in-between Fontan stages and after conclusion of Fontan surgery may occur and should be promptly diagnosed and addressed accordingly. Several other cardiac abnormalities unrelated to the initially identified heart defects may manifest in adulthood, and they should also be treated. MDPI 2023-04-17 /pmc/articles/PMC10137016/ /pubmed/37189988 http://dx.doi.org/10.3390/children10040739 Text en © 2023 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Rao, P. Syamasundar
Therapy of Patients with Cardiac Malposition
title Therapy of Patients with Cardiac Malposition
title_full Therapy of Patients with Cardiac Malposition
title_fullStr Therapy of Patients with Cardiac Malposition
title_full_unstemmed Therapy of Patients with Cardiac Malposition
title_short Therapy of Patients with Cardiac Malposition
title_sort therapy of patients with cardiac malposition
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137016/
https://www.ncbi.nlm.nih.gov/pubmed/37189988
http://dx.doi.org/10.3390/children10040739
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