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Evaluation of 2D and 3D Erythroid Differentiation Protocols Using Sickle Cell Disease and Healthy Donor Induced Pluripotent Stem Cells

Background: Sickle cell disease (SCD) is a highly prevalent genetic disease caused by a point mutation in the HBB gene, which can lead to chronic hemolytic anemia and vaso-occlusive events. Patient-derived induced pluripotent stem cells (iPSCs) hold promise for the development of novel predictive me...

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Detalles Bibliográficos
Autores principales:	Martins, Gabriele Louise Soares, Nonaka, Carolina Kymie Vasques, Rossi, Erik Aranha, de Lima, Adne Vitória Rocha, Adanho, Corynne Stephanie Ahouefa, Oliveira, Moisés Santana, Yahouedehou, Setondji Cocou Modeste Alexandre, de Souza, Clarissa Lima e Moura, Gonçalves, Marilda de Souza, Paredes, Bruno Diaz, Souza, Bruno Solano de Freitas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137038/ https://www.ncbi.nlm.nih.gov/pubmed/37190030 http://dx.doi.org/10.3390/cells12081121

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