Cargando…

Inhibitory Effect of Phosphorothioate Oligonucleotide Complementary to G6PD mRNA on Murine Melanoma

In terms of the incidence among all tumors, skin cancer is on top, with the most deadly among them being melanoma. The search for new therapeutic agents to combat melanoma is very relevant. In our opinion, antisense oligonucleotides (ASO) aimed at suppressing the genes responsible for their viabilit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yurchenko, Kseniya A., Laikova, Kateryna V., Golovkin, Ilya O., Novikov, Ilya A., Yurchenko, Alyona A., Makalish, Tatyana P., Oberemok, Volodymyr V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137061/ https://www.ncbi.nlm.nih.gov/pubmed/37185731 http://dx.doi.org/10.3390/cimb45040207

Ejemplares similares

Anti-Rheumatic Effect of Antisense Oligonucleotide Cytos-11 Targeting TNF-α Expression
por: Makalish, Tatyana P., et al.
Publicado: (2021)

SARS-CoV-2 will continue to circulate in the human population: no worries with state-of-the-art research and dependably useful results
por: Oberemok, Volodymyr V., et al.
Publicado: (2020)

SARS-CoV-2 will continue to circulate in the human population: an opinion from the point of view of the virus-host relationship
por: Oberemok, Volodymyr V., et al.
Publicado: (2020)

Oligonucleotide Insecticides for Green Agriculture: Regulatory Role of Contact DNA in Plant–Insect Interactions
por: Oberemok, Volodymyr V., et al.
Publicado: (2022)

Advances in the Understanding of Skin Cancer: Ultraviolet Radiation, Mutations, and Antisense Oligonucleotides as Anticancer Drugs
por: Laikova, Kateryna V., et al.
Publicado: (2019)

Icerya purchasi Maskell (Hemiptera: Monophlebidae) Control Using Low Carbon Footprint Oligonucleotide Insecticides
por: Gal’chinsky, Nikita V., et al.
Publicado: (2023)

Post-genomic platform for development of oligonucleotide vaccines against RNA viruses: diamond cuts diamond
por: Oberemok, V. V., et al.
Publicado: (2022)

Perfect Complementarity Mechanism for Aphid Control: Oligonucleotide Insecticide Macsan-11 Selectively Causes High Mortality Rate for Macrosiphoniella sanborni Gillette
por: Puzanova, Yelizaveta V., et al.
Publicado: (2023)

Rheumatoid Arthritis Has Won the Battle but Not the War: How Many Joints Will We Save Tomorrow?
por: Oberemok, Volodymyr V., et al.
Publicado: (2023)

Data for increase of Lymantria dispar male survival after topical application of single-stranded RING domain fragment of IAP-3 gene of its nuclear polyhedrosis virus
por: Oberemok, Volodymyr V., et al.
Publicado: (2016)

Phosphorothioate modified oligonucleotide–protein interactions
por: Crooke, Stanley T, et al.
Publicado: (2020)

SARS-CoV-2 will constantly sweep its tracks: a vaccine containing CpG motifs in ‘lasso’ for the multi-faced virus
por: Oberemok, V. V., et al.
Publicado: (2020)

DNA insecticide developed from the Lymantria dispar 5.8S ribosomal RNA gene provides a novel biotechnology for plant protection
por: Oberemok, Volodymyr V., et al.
Publicado: (2019)

Four Most Pathogenic Superfamilies of Insect Pests of Suborder Sternorrhyncha: Invisible Superplunderers of Plant Vitality
por: Oberemok, Volodymyr V., et al.
Publicado: (2023)

Electronic Structures of LNA Phosphorothioate Oligonucleotides
por: Bohr, Henrik G., et al.
Publicado: (2017)

Molecular Alliance of Lymantria dispar Multiple Nucleopolyhedrovirus and a Short Unmodified Antisense Oligonucleotide of Its Anti-Apoptotic IAP-3 Gene: A Novel Approach for Gypsy Moth Control
por: Oberemok, Volodymyr V., et al.
Publicado: (2017)

Mesyl phosphoramidate antisense oligonucleotides as an alternative to phosphorothioates with improved biochemical and biological properties
por: Miroshnichenko, S. K., et al.
Publicado: (2019)

Selective Covalent Conjugation of Phosphorothioate DNA Oligonucleotides with Streptavidin
por: Rabe, Kersten S., et al.
Publicado: (2011)

Investigation of factors influencing the separation of diastereomers of phosphorothioated oligonucleotides
por: Enmark, Martin, et al.
Publicado: (2019)

Oligonucleotide Phosphorothioates Enter Cells by Thiol‐Mediated Uptake
por: Laurent, Quentin, et al.
Publicado: (2021)

Solid-Phase Synthesis of Boranophosphate/Phosphorothioate/Phosphate Chimeric Oligonucleotides and Their Potential as Antisense Oligonucleotides
por: Takahashi, Yuhei, et al.
Publicado: (2021)

DNA Oligonucleotides as Antivirals and Vaccine Constituents against SARS Coronaviruses: A Prospective Tool for Immune System Tuning
por: Oberemok, Volodymyr V., et al.
Publicado: (2023)

Identification and characterization of intracellular proteins that bind oligonucleotides with phosphorothioate linkages
por: Liang, Xue-hai, et al.
Publicado: (2015)

Solid-Phase Synthesis of Phosphorothioate/Phosphonothioate and Phosphoramidate/Phosphonamidate Oligonucleotides
por: Kostov, Ondřej, et al.
Publicado: (2019)

A Versatile and Convenient Synthesis of (34)S‐Labeled Phosphorothioate Oligonucleotides
por: Stulz, Rouven, et al.
Publicado: (2018)

Preclinical PK and PD Studies on 2′-O-Methyl-phosphorothioate RNA Antisense Oligonucleotides in the mdx Mouse Model
por: Heemskerk, Hans, et al.
Publicado: (2010)

Anti-coronavirus vaccines will not accelerate the transition of humanity to a non-pandemic period, but the pandemic will take fewer victims
por: Oberemok, V. V., et al.
Publicado: (2022)

Phosphorothioate oligonucleotides, suramin and heparin inhibit DNA-dependent protein kinase activity
por: Hosoi, Y, et al.
Publicado: (2002)

Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytes
por: Koller, Erich, et al.
Publicado: (2011)

Analytical and preparative separation of phosphorothioated oligonucleotides: columns and ion-pair reagents
por: Enmark, Martin, et al.
Publicado: (2019)

Controlled sulfur-based engineering confers mouldability to phosphorothioate antisense oligonucleotides
por: Genna, Vito, et al.
Publicado: (2023)

Antiviral effect of phosphorothioate oligodeoxyribonucleotides complementary to human immunodeficiency virus
por: Kim, Sang-Gug, et al.
Publicado: (1995)

Nucleoside alpha-thiotriphosphates, polymerases and the exonuclease III analysis of oligonucleotides containing phosphorothioate linkages
por: Yang, Zunyi, et al.
Publicado: (2007)

Nucleic acid binding proteins affect the subcellular distribution of phosphorothioate antisense oligonucleotides
por: Bailey, Jeffrey K., et al.
Publicado: (2017)

Membrane Destabilization Induced by Lipid Species Increases Activity of Phosphorothioate-Antisense Oligonucleotides
por: Wang, Shiyu, et al.
Publicado: (2018)

Developing predictive hybridization models for phosphorothioate oligonucleotides using high-resolution melting
por: Wang, Siyuan S., et al.
Publicado: (2022)

Stereo-Controlled Liquid Phase Synthesis of Phosphorothioate Oligonucleotides on a Soluble Support
por: Rosenqvist, Petja, et al.
Publicado: (2023)

An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides
por: Baker, Ysobel R., et al.
Publicado: (2022)

Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor
por: Schmidt, Karsten, et al.
Publicado: (2017)

Long-term Exon Skipping Studies With 2′-O-Methyl Phosphorothioate Antisense Oligonucleotides in Dystrophic Mouse Models
por: Tanganyika-de Winter, Christa L, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_1ecohr3237151mknq95qgh1aue