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Steatosis and Metabolic Disorders Associated with Synergistic Activation of the CAR/RXR Heterodimer by Pesticides

The nuclear receptor, constitutive androstane receptor (CAR), which forms a heterodimer with the retinoid X receptor (RXR), was initially reported as a transcription factor that regulates hepatic genes involved in detoxication and energy metabolism. Different studies have shown that CAR activation r...

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Detalles Bibliográficos
Autores principales: Dauwe, Yannick, Mary, Lucile, Oliviero, Fabiana, Grimaldi, Marina, Balaguer, Patrick, Gayrard, Véronique, Mselli-Lakhal, Laïla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137125/
https://www.ncbi.nlm.nih.gov/pubmed/37190111
http://dx.doi.org/10.3390/cells12081201