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Steatosis and Metabolic Disorders Associated with Synergistic Activation of the CAR/RXR Heterodimer by Pesticides
The nuclear receptor, constitutive androstane receptor (CAR), which forms a heterodimer with the retinoid X receptor (RXR), was initially reported as a transcription factor that regulates hepatic genes involved in detoxication and energy metabolism. Different studies have shown that CAR activation r...
Autores principales: | Dauwe, Yannick, Mary, Lucile, Oliviero, Fabiana, Grimaldi, Marina, Balaguer, Patrick, Gayrard, Véronique, Mselli-Lakhal, Laïla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137125/ https://www.ncbi.nlm.nih.gov/pubmed/37190111 http://dx.doi.org/10.3390/cells12081201 |
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