Timing of Interleukin-4 Stimulation of Macrophages Determines Their Anti-Microbial Activity during Infection with Salmonella enterica Serovar Typhimurium

Priming of macrophages with interferon-gamma (IFNγ) or interleukin-4 (IL-4) leads to polarisation into pro-inflammatory or anti-inflammatory subtypes, which produce key enzymes such as inducible nitric oxide synthase (iNOS) and arginase 1 (ARG1), respectively, and in this way determine host response...

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Detalles Bibliográficos
Autores principales: Brigo, Natascha, Neumaier, Emely, Pfeifhofer-Obermair, Christa, Grubwieser, Philipp, Engl, Sabine, Berger, Sylvia, Seifert, Markus, Reinstadler, Vera, Oberacher, Herbert, Weiss, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137269/
https://www.ncbi.nlm.nih.gov/pubmed/37190073
http://dx.doi.org/10.3390/cells12081164

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