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How Well Can We Infer Selection Benefits and Mutation Rates from Allele Frequencies?
Experimentalists observe allele frequency distributions and try to infer mutation rates and selection coefficients. How easy is this? We calculate limits to their ability in the context of the Wright-Fisher model by first finding the maximal amount of information that can be acquired using allele fr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137336/ https://www.ncbi.nlm.nih.gov/pubmed/37190403 http://dx.doi.org/10.3390/e25040615 |