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Highly Efficient A-to-G Editing in PFFs via Multiple ABEs

Cytosine base editors (CBEs) and adenine base editors (ABEs) are recently developed CRISPR-mediated genome-editing tools that do not introduce double-strand breaks. In this study, five ABEs, ABE7.10, ABEmax, NG-ABEmax, ABE8e and NG-ABE8e, were used to generate A-to-G (T-to-C) conversions in five gen...

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Detalles Bibliográficos
Autores principales: Jing, Qiqi, Liu, Weiwei, Jiang, Haoyun, Liao, Yaya, Yang, Qiang, Xing, Yuyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137487/
https://www.ncbi.nlm.nih.gov/pubmed/37107666
http://dx.doi.org/10.3390/genes14040908