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A Nanoclay-Enhanced Hydrogel for Self-Adhesive Wearable Electrophysiology Electrodes with High Sensitivity and Stability

Hydrogel-based wet electrodes are the most important biosensors for electromyography (EMG), electrocardiogram (ECG), and electroencephalography (EEG); but, are limited by poor strength and weak adhesion. Herein, a new nanoclay-enhanced hydrogel (NEH) has been reported, which can be fabricated simply...

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Autores principales: Wang, Fushuai, Yang, Lang, Sun, Ye, Cai, Yiming, Xu, Xin, Liu, Zhenzhong, Liu, Qijie, Zhao, Hongliang, Ma, Chunxin, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137570/
https://www.ncbi.nlm.nih.gov/pubmed/37102935
http://dx.doi.org/10.3390/gels9040323
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author Wang, Fushuai
Yang, Lang
Sun, Ye
Cai, Yiming
Xu, Xin
Liu, Zhenzhong
Liu, Qijie
Zhao, Hongliang
Ma, Chunxin
Liu, Jun
author_facet Wang, Fushuai
Yang, Lang
Sun, Ye
Cai, Yiming
Xu, Xin
Liu, Zhenzhong
Liu, Qijie
Zhao, Hongliang
Ma, Chunxin
Liu, Jun
author_sort Wang, Fushuai
collection PubMed
description Hydrogel-based wet electrodes are the most important biosensors for electromyography (EMG), electrocardiogram (ECG), and electroencephalography (EEG); but, are limited by poor strength and weak adhesion. Herein, a new nanoclay-enhanced hydrogel (NEH) has been reported, which can be fabricated simply by dispersing nanoclay sheets (Laponite XLS) into the precursor solution (containing acrylamide, N, N′-Methylenebisacrylamide, ammonium persulfate, sodium chloride, glycerin) and then thermo-polymerizing at 40 °C for 2 h. This NEH, with a double-crosslinked network, has nanoclay-enhanced strength and self-adhesion for wet electrodes with excellent long-term stability of electrophysiology signals. First of all, among existing hydrogels for biological electrodes, this NEH has outstanding mechanical performance (93 kPa of tensile strength and 1326% of breaking elongation) and adhesion (14 kPa of adhesive force), owing to the double-crosslinked network of the NEH and the composited nanoclay, respectively. Furthermore, this NEH can still maintain a good water-retaining property (it can remain at 65.4% of its weight after 24 h at 40 °C and 10% humidity) for excellent long-term stability of signals, on account of the glycerin in the NEH. In the stability test of skin–electrode impedance at the forearm, the impedance of the NEH electrode can be stably kept at about 100 kΩ for more than 6 h. As a result, this hydrogel-based electrode can be applied for a wearable self-adhesive monitor to highly sensitively and stably acquire EEG/ECG electrophysiology signals of the human body over a relatively long time. This work provides a promising wearable self-adhesive hydrogel-based electrode for electrophysiology sensing; which, will also inspire the development of new strategies to improve electrophysiological sensors.
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spelling pubmed-101375702023-04-28 A Nanoclay-Enhanced Hydrogel for Self-Adhesive Wearable Electrophysiology Electrodes with High Sensitivity and Stability Wang, Fushuai Yang, Lang Sun, Ye Cai, Yiming Xu, Xin Liu, Zhenzhong Liu, Qijie Zhao, Hongliang Ma, Chunxin Liu, Jun Gels Article Hydrogel-based wet electrodes are the most important biosensors for electromyography (EMG), electrocardiogram (ECG), and electroencephalography (EEG); but, are limited by poor strength and weak adhesion. Herein, a new nanoclay-enhanced hydrogel (NEH) has been reported, which can be fabricated simply by dispersing nanoclay sheets (Laponite XLS) into the precursor solution (containing acrylamide, N, N′-Methylenebisacrylamide, ammonium persulfate, sodium chloride, glycerin) and then thermo-polymerizing at 40 °C for 2 h. This NEH, with a double-crosslinked network, has nanoclay-enhanced strength and self-adhesion for wet electrodes with excellent long-term stability of electrophysiology signals. First of all, among existing hydrogels for biological electrodes, this NEH has outstanding mechanical performance (93 kPa of tensile strength and 1326% of breaking elongation) and adhesion (14 kPa of adhesive force), owing to the double-crosslinked network of the NEH and the composited nanoclay, respectively. Furthermore, this NEH can still maintain a good water-retaining property (it can remain at 65.4% of its weight after 24 h at 40 °C and 10% humidity) for excellent long-term stability of signals, on account of the glycerin in the NEH. In the stability test of skin–electrode impedance at the forearm, the impedance of the NEH electrode can be stably kept at about 100 kΩ for more than 6 h. As a result, this hydrogel-based electrode can be applied for a wearable self-adhesive monitor to highly sensitively and stably acquire EEG/ECG electrophysiology signals of the human body over a relatively long time. This work provides a promising wearable self-adhesive hydrogel-based electrode for electrophysiology sensing; which, will also inspire the development of new strategies to improve electrophysiological sensors. MDPI 2023-04-11 /pmc/articles/PMC10137570/ /pubmed/37102935 http://dx.doi.org/10.3390/gels9040323 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wang, Fushuai
Yang, Lang
Sun, Ye
Cai, Yiming
Xu, Xin
Liu, Zhenzhong
Liu, Qijie
Zhao, Hongliang
Ma, Chunxin
Liu, Jun
A Nanoclay-Enhanced Hydrogel for Self-Adhesive Wearable Electrophysiology Electrodes with High Sensitivity and Stability
title A Nanoclay-Enhanced Hydrogel for Self-Adhesive Wearable Electrophysiology Electrodes with High Sensitivity and Stability
title_full A Nanoclay-Enhanced Hydrogel for Self-Adhesive Wearable Electrophysiology Electrodes with High Sensitivity and Stability
title_fullStr A Nanoclay-Enhanced Hydrogel for Self-Adhesive Wearable Electrophysiology Electrodes with High Sensitivity and Stability
title_full_unstemmed A Nanoclay-Enhanced Hydrogel for Self-Adhesive Wearable Electrophysiology Electrodes with High Sensitivity and Stability
title_short A Nanoclay-Enhanced Hydrogel for Self-Adhesive Wearable Electrophysiology Electrodes with High Sensitivity and Stability
title_sort nanoclay-enhanced hydrogel for self-adhesive wearable electrophysiology electrodes with high sensitivity and stability
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137570/
https://www.ncbi.nlm.nih.gov/pubmed/37102935
http://dx.doi.org/10.3390/gels9040323
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