Chronic Stress Alters Hippocampal Renin-Angiotensin-Aldosterone System Component Expression in an Aged Rat Model of Wolfram Syndrome

Biallelic mutations in the gene encoding WFS1 underlie the development of Wolfram syndrome (WS), a rare neurodegenerative disorder with no available cure. We have previously shown that Wfs1 deficiency can impair the functioning of the renin-angiotensin-aldosterone system (RAAS). The expression of tw...

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Detalles Bibliográficos
Autores principales: Punapart, Marite, Reimets, Riin, Seppa, Kadri, Kirillov, Silvia, Gaur, Nayana, Eskla, Kattri-Liis, Jagomäe, Toomas, Vasar, Eero, Plaas, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137641/
https://www.ncbi.nlm.nih.gov/pubmed/37107585
http://dx.doi.org/10.3390/genes14040827

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