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Factors regulating Hb F synthesis in thalassemic diseases
BACKGROUND: The thalassemic syndromes originate from mutations of the globin genes that cause, besides the characteristic clinical picture, also an increased Hb F amount. It is not yet clear if there are more factors, besides the beta globin genotype, determining the Hb F production. We have tried t...
Autores principales: | Mastropietro, Fabrizio, Modiano, Guido, Cappabianca, Maria Pia, Foglietta, Enrica, D'Asero, Carmelo, Mezzabotta, Mauro, Ponzini, Donatella, Maffei, Laura, Amato, Antonio, Lerone, Maria, Grisanti, Paola, Di Biagio, Paola, Rinaldi, Silvana, Bianco, Ida |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC101377/ https://www.ncbi.nlm.nih.gov/pubmed/11943067 http://dx.doi.org/10.1186/1471-2326-2-2 |
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