Interaction between KLOTHO-VS Heterozygosity and APOE ε4 Allele Predicts Rate of Cognitive Decline in Late-Onset Alzheimer’s Disease

KLOTHO-VS heterozygosity (KL-VS(het+)) promotes longevity and protects against cognitive decline in aging. To determine whether KL-VS(het+) mitigates Alzheimer’s disease (AD) progression, we used longitudinal linear-mixed models to compare the rate of change in multiple cognitive measures in AD pati...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xi Richard, Shao, Yongzhao, Sadowski, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137709/
https://www.ncbi.nlm.nih.gov/pubmed/37107675
http://dx.doi.org/10.3390/genes14040917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137709/
https://www.ncbi.nlm.nih.gov/pubmed/37107675
http://dx.doi.org/10.3390/genes14040917

Ejemplares similares