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Interaction between KLOTHO-VS Heterozygosity and APOE ε4 Allele Predicts Rate of Cognitive Decline in Late-Onset Alzheimer’s Disease

KLOTHO-VS heterozygosity (KL-VS(het+)) promotes longevity and protects against cognitive decline in aging. To determine whether KL-VS(het+) mitigates Alzheimer’s disease (AD) progression, we used longitudinal linear-mixed models to compare the rate of change in multiple cognitive measures in AD pati...

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Detalles Bibliográficos
Autores principales:	Chen, Xi Richard, Shao, Yongzhao, Sadowski, Martin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137709/ https://www.ncbi.nlm.nih.gov/pubmed/37107675 http://dx.doi.org/10.3390/genes14040917

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