Targeted Modulation of Chicken Genes In Vitro Using CRISPRa and CRISPRi Toolkit

Engineering of clustered regularly interspaced short palindromic repeats (CRISPR) and the CRISPR-associated protein 9 (Cas9) system has enabled versatile applications of CRISPR beyond targeted DNA cleavage. Combination of nuclease-deactivated Cas9 (dCas9) and transcriptional effector domains allows...

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Detalles Bibliográficos
Autores principales: Chapman, Brittany, Han, Jeong Hoon, Lee, Hong Jo, Ruud, Isabella, Kim, Tae Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137795/
https://www.ncbi.nlm.nih.gov/pubmed/37107664
http://dx.doi.org/10.3390/genes14040906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137795/
https://www.ncbi.nlm.nih.gov/pubmed/37107664
http://dx.doi.org/10.3390/genes14040906

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