Cargando…

cDCDD‐NRP is consistent with US legal standards for determining death

Donation after circulatory determination of death (DCDD) has increased organ donation rates in the US over the past decade within an established legal framework, which is consistent with and supports individual and family decisions regarding organ donation in the context of end‐of‐life care. A new a...

Descripción completa

Detalles Bibliográficos
Autores principales: Adams, Bradley L., Brenner, Lauren, Levan, Macey, Parent, Brendan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138106/
https://www.ncbi.nlm.nih.gov/pubmed/35510751
http://dx.doi.org/10.1111/ajt.17083
_version_ 1785032628132380672
author Adams, Bradley L.
Brenner, Lauren
Levan, Macey
Parent, Brendan
author_facet Adams, Bradley L.
Brenner, Lauren
Levan, Macey
Parent, Brendan
author_sort Adams, Bradley L.
collection PubMed
description Donation after circulatory determination of death (DCDD) has increased organ donation rates in the US over the past decade within an established legal framework, which is consistent with and supports individual and family decisions regarding organ donation in the context of end‐of‐life care. A new application, controlled DCDD donation utilizing thoracoabdominal normothermic regional perfusion (NRP) protocols (cDCDD‐NRP), provides the opportunity to maximize a donation decision by recovering additional organs for transplant, including the heart, and to limit the detrimental impact of warm ischemic time by perfusing organs in situ following the declaration of circulatory death. In this viewpoint, we narrate our rationale for why cDCDD‐NRP is consistent within the existing legal framework for organ donation in the United States and recommend no changes to the Uniform Determination of Death Act.
format Online
Article
Text
id pubmed-10138106
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-101381062023-04-28 cDCDD‐NRP is consistent with US legal standards for determining death Adams, Bradley L. Brenner, Lauren Levan, Macey Parent, Brendan Am J Transplant Personal Viewpoint Donation after circulatory determination of death (DCDD) has increased organ donation rates in the US over the past decade within an established legal framework, which is consistent with and supports individual and family decisions regarding organ donation in the context of end‐of‐life care. A new application, controlled DCDD donation utilizing thoracoabdominal normothermic regional perfusion (NRP) protocols (cDCDD‐NRP), provides the opportunity to maximize a donation decision by recovering additional organs for transplant, including the heart, and to limit the detrimental impact of warm ischemic time by perfusing organs in situ following the declaration of circulatory death. In this viewpoint, we narrate our rationale for why cDCDD‐NRP is consistent within the existing legal framework for organ donation in the United States and recommend no changes to the Uniform Determination of Death Act. John Wiley and Sons Inc. 2022-05-18 2022-10 /pmc/articles/PMC10138106/ /pubmed/35510751 http://dx.doi.org/10.1111/ajt.17083 Text en © 2022 The Authors. American Journal of Transplantation published by Wiley Periodicals LLC on behalf of The American Society of Transplantation and the American Society of Transplant Surgeons https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Personal Viewpoint
Adams, Bradley L.
Brenner, Lauren
Levan, Macey
Parent, Brendan
cDCDD‐NRP is consistent with US legal standards for determining death
title cDCDD‐NRP is consistent with US legal standards for determining death
title_full cDCDD‐NRP is consistent with US legal standards for determining death
title_fullStr cDCDD‐NRP is consistent with US legal standards for determining death
title_full_unstemmed cDCDD‐NRP is consistent with US legal standards for determining death
title_short cDCDD‐NRP is consistent with US legal standards for determining death
title_sort cdcdd‐nrp is consistent with us legal standards for determining death
topic Personal Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138106/
https://www.ncbi.nlm.nih.gov/pubmed/35510751
http://dx.doi.org/10.1111/ajt.17083
work_keys_str_mv AT adamsbradleyl cdcddnrpisconsistentwithuslegalstandardsfordeterminingdeath
AT brennerlauren cdcddnrpisconsistentwithuslegalstandardsfordeterminingdeath
AT levanmacey cdcddnrpisconsistentwithuslegalstandardsfordeterminingdeath
AT parentbrendan cdcddnrpisconsistentwithuslegalstandardsfordeterminingdeath