Cargando…

Evidence of Association between CTLA-4 Gene Polymorphisms and Colorectal Cancers in Saudi Patients

Cytotoxic T lymphocyte antigen-4 (CTLA-4) has been identified as an immunosuppressive molecule involved in the negative regulation of T cells. It is highly expressed in several types of autoimmune diseases and cancers including colorectal cancer (CRC). (1) Objective: To explore the association betwe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Al-Harbi, Nouf, Abdulla, Maha-Hamadien, Vaali-Mohammed, Mansoor-Ali, Bin Traiki, Thamer, Alswayyed, Mohammed, Al-Obeed, Omar, Abid, Islem, Al-Omar, Suliman, Mansour, Lamjed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138150/ https://www.ncbi.nlm.nih.gov/pubmed/37107632 http://dx.doi.org/10.3390/genes14040874

Ejemplares similares

Rs10204525 Polymorphism of the Programmed Death (PD-1) Gene Is Associated with Increased Risk in a Saudi Arabian Population with Colorectal Cancer
por: Al-Harbi, Nouf, et al.
Publicado: (2022)

IL-17 and colorectal cancer risk in the Middle East: gene polymorphisms and expression
por: Al Obeed, Omar A, et al.
Publicado: (2018)

Polymorphisms of tumor necrosis factor alpha in Middle Eastern population with colorectal cancer
por: Hamadien, Maha-Abdulla, et al.
Publicado: (2015)

Association of Vitamin D Receptor Gene Polymorphisms with Colorectal Cancer in a Saudi Arabian Population
por: Alkhayal, Khayal A., et al.
Publicado: (2016)

A novel coordination complex of platinum (PT) induces cell death in colorectal cancer by altering redox balance and modulating MAPK pathway
por: Al-Khayal, Khayal, et al.
Publicado: (2020)

Correction to: A novel coordination complex of platinum (PT) induces cell death in colorectal cancer by altering redox balance and modulating MAPK pathway
por: Al-Khayal, Khayal, et al.
Publicado: (2020)

Targeting MUCL1 protein inhibits cell proliferation and EMT by deregulating β-catenin and increases irinotecan sensitivity in colorectal cancer
por: Abdulla, Maha, et al.
Publicado: (2022)

Lymphangioma of the Ileocecal Valve Clinically Masquerading as a Submucosal Small Intestinal Gist: Report of a Case and Literature Review
por: Al-Obeed, Omar A., et al.
Publicado: (2014)

Prevalence of vasovagal syncope following bariatric surgery
por: Al Obeed, Omar A., et al.
Publicado: (2021)

The Anticancer Effects of the Pro-Apoptotic Benzofuran-Isatin Conjugate (5a) Are Associated With p53 Upregulation and Enhancement of Conventional Chemotherapeutic Drug Efficiency in Colorectal Cancer Cell Lines
por: Vaali-Mohammed, Mansoor-Ali, et al.
Publicado: (2022)

Identification of the TP53-induced glycolysis and apoptosis regulator in various stages of colorectal cancer patients
por: AL-KHAYAL, KHAYAL, et al.
Publicado: (2016)

The platinum coordination complex inhibits cell invasion-migration and epithelial-to-mesenchymal transition by altering the TGF-β-SMAD pathway in colorectal cancer
por: Abdulla, Maha-Hamadien, et al.
Publicado: (2023)

5-year oncological outcomes in left-sided malignant colonic obstruction: stent as bridge to surgery
por: Alhassan, Noura S, et al.
Publicado: (2023)

Novel derivative of aminobenzenesulfonamide (3c) induces apoptosis in colorectal cancer cells through ROS generation and inhibits cell migration
por: Al-Khayal, Khayal, et al.
Publicado: (2017)

Herbal melanin inhibits colorectal cancer cell proliferation by altering redox balance, inducing apoptosis, and modulating MAPK signaling
por: Al-Obeed, Omar, et al.
Publicado: (2020)

Oncological outcomes of elective versus emergency surgery for colon cancer: A tertiary academic center experience
por: Bin Traiki, Thamer A., et al.
Publicado: (2023)

Cathepsin B expression in colorectal cancer in a Middle East population: Potential value as a tumor biomarker for late disease stages
por: Abdulla, Maha-Hamadien, et al.
Publicado: (2017)

Novel quinazoline-based sulfonamide derivative (3D) induces apoptosis in colorectal cancer by inhibiting JAK2–STAT3 pathway
por: Al-Obeed, Omar, et al.
Publicado: (2018)

Differential expression of mucins in Middle Eastern patients with colorectal cancer
por: AL-KHAYAL, KHAYAL, et al.
Publicado: (2016)

A 66-Year-Old Man Presenting with Port-Site Metastatic Gastric Adenocarcinoma 4 Years After Laparoscopic Resection of a Rectal Adenocarcinoma
por: Hakami, Riyadh, et al.
Publicado: (2022)

Colorectal cancer-related resource utilization and healthcare costs in Saudi Arabia
por: Balkhi, Bander, et al.
Publicado: (2023)

TLTF in Cerebrospinal Fluid for Detection and Staging of T. b. gambiense Infection
por: Abdulla, Maha-Hamadien, et al.
Publicado: (2013)

Hemorrhagic Necrotizing Cholecystitis With Cholecystocolonic Fistula: A Case Report
por: AlQahtani, Awadh, et al.
Publicado: (2022)

Long-term outcomes after complete mesocolic excision for colon cancer at a tertiary care center in Saudi Arabia
por: Alharbi, Reem A., et al.
Publicado: (2020)

A Constitutional Mismatch Repair Deficiency Syndrome Presented With an Advanced Rectal Cancer in a Juvenile Female: A Case Report and Literature Review
por: AlAli, Mohammed N, et al.
Publicado: (2022)

Cystic Ovarian Leiomyoma in a Patient with Progressive Abdominal Pain
por: Alshwairikh, Khaloud, et al.
Publicado: (2021)

Short-term outcomes after self-expandable metal stent insertion for obstructing colon cancer: a retrospective cohort study
por: Alkhayal, Khayal Abdulmalik, et al.
Publicado: (2020)

Impact of COVID-19 pandemic on patient satisfaction and surgical outcomes: A retrospective and cross sectional study
por: Bin Traiki, Thamer A., et al.
Publicado: (2020)

Expression profiling of selected microRNA signatures in plasma and tissues of Saudi colorectal cancer patients by qPCR
por: AL-SHEIKH, YAZEED A., et al.
Publicado: (2016)

Perforated mucocele of the appendix in the left upper quadrant: A challenging anatomy and an improvised surgical technique
por: Alhassan, Basmah Faris, et al.
Publicado: (2019)

Genotypic diversity of the Killer Cell Immunoglobulin-like Receptors (KIR) and their HLA class I Ligands in a Saudi population
por: Omar, Suliman Y. Al, et al.
Publicado: (2016)

Trends in infant nutrition in Saudi Arabia: compliance with WHO recommendations
por: El Mouzan, Mohammed I., et al.
Publicado: (2009)

Community knowledge and awareness of colorectal cancer and screening tools: Community-based survey of 1,912 residents of Riyadh
por: Alaqel, Maram Abdullah, et al.
Publicado: (2021)

Single-incision laparoscopic colorectal surgery: a report of 33 cases in Saudi Arabia
por: Zubaidi, Ahmad, et al.
Publicado: (2016)

A Perforated Colonic Neuroendocrine Tumor with Liver Metastasis: A Case Report and Literature Review
por: Alshammari, Turki F., et al.
Publicado: (2019)

Awareness regarding childhood asthma in Saudi Arabia
por: Al-Harbi, Saleh, et al.
Publicado: (2016)

Liver Size in Saudi Children and Adolescents
por: El Mouzan, Mohammad I., et al.
Publicado: (2009)

The impact of preoperative total parenteral nutrition on the surgical complications of Crohn’s disease: A retrospective cohort study
por: Bin Traiki, Thamer A., et al.
Publicado: (2022)

The changing face of healthcare in Saudi Arabia
por: Walston, Stephen, et al.
Publicado: (2008)

Colorectal Cancer Liver Metastasis Trends in the Kingdom of Saudi Arabia
por: Hassanain, Mazen, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_f32ff3atfbv2rjavgq9ik04kcd