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4’-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses

Influenza outbreaks are associated with substantial morbidity, mortality and economic burden. Next generation antivirals are needed to treat seasonal infections and prepare against zoonotic spillover of avian influenza viruses with pandemic potential. Having previously identified oral efficacy of th...

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Detalles Bibliográficos
Autores principales: Lieber, Carolin M., Aggarwal, Megha, Yoon, Jeong-Joong, Cox, Robert M., Kang, Hae-Ji, Sourimant, Julien, Toots, Mart, Johnson, Scott K., Jones, Cheryl A., Sticher, Zachary M., Kolykhalov, Alexander A., Saindane, Manohar T., Tompkins, Stephen M., Planz, Oliver, Painter, George R., Natchus, Michael G., Sakamoto, Kaori, Plemper, Richard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138230/
https://www.ncbi.nlm.nih.gov/pubmed/37068076
http://dx.doi.org/10.1371/journal.ppat.1011342