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Redox mechanisms and their pathological role in prion diseases: The road to ruin

Prion diseases, also known as transmissible spongiform encephalopathies, are rare, progressive, and fatal neurodegenerative disorders, which are caused by the accumulation of the misfolded cellular prion protein (PrP(C)). The resulting cytotoxic prion species, referred to as the scrapie prion isofor...

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Detalles Bibliográficos
Autores principales: Spiers, Jereme G., Chen, Hsiao-Jou Cortina, Steinert, Joern R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138251/
https://www.ncbi.nlm.nih.gov/pubmed/37104170
http://dx.doi.org/10.1371/journal.ppat.1011309