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Redox mechanisms and their pathological role in prion diseases: The road to ruin
Prion diseases, also known as transmissible spongiform encephalopathies, are rare, progressive, and fatal neurodegenerative disorders, which are caused by the accumulation of the misfolded cellular prion protein (PrP(C)). The resulting cytotoxic prion species, referred to as the scrapie prion isofor...
Autores principales: | Spiers, Jereme G., Chen, Hsiao-Jou Cortina, Steinert, Joern R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138251/ https://www.ncbi.nlm.nih.gov/pubmed/37104170 http://dx.doi.org/10.1371/journal.ppat.1011309 |
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