MFGE8 links absorption of dietary fatty acids with catabolism of enterocyte lipid stores through HNF4γ-dependent transcription of CES enzymes

Enterocytes modulate the extent of postprandial lipemia by storing dietary fats in cytoplasmic lipid droplets (cLDs). We have previously shown that the integrin ligand MFGE8 links absorption of dietary fats with activation of triglyceride (TG) hydrolases that catabolize cLDs for chylomicron producti...

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Detalles Bibliográficos
Autores principales: Datta, Ritwik, Gholampour, Mohammad A., Yang, Christopher D., Volk, Regan, Lin, Sinan, Podolsky, Michael J., Arnold, Thomas, Rieder, Florian, Zaro, Balyn W., Verzi, Michael, Lehner, Richard, Abumrad, Nada, Lizama, Carlos O., Atabai, Kamran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138282/
https://www.ncbi.nlm.nih.gov/pubmed/36924494
http://dx.doi.org/10.1016/j.celrep.2023.112249

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