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Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications

Chitosan is a promising naturally derived polysaccharide to be used in hydrogel forms for pharmaceutical and biomedical applications. The multifunctional chitosan-based hydrogels have attractive properties such as the ability to encapsulate, carry, and release the drug, biocompatibility, biodegradab...

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Detalles Bibliográficos
Autores principales: Taokaew, Siriporn, Kaewkong, Worasak, Kriangkrai, Worawut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138304/
https://www.ncbi.nlm.nih.gov/pubmed/37102889
http://dx.doi.org/10.3390/gels9040277
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author Taokaew, Siriporn
Kaewkong, Worasak
Kriangkrai, Worawut
author_facet Taokaew, Siriporn
Kaewkong, Worasak
Kriangkrai, Worawut
author_sort Taokaew, Siriporn
collection PubMed
description Chitosan is a promising naturally derived polysaccharide to be used in hydrogel forms for pharmaceutical and biomedical applications. The multifunctional chitosan-based hydrogels have attractive properties such as the ability to encapsulate, carry, and release the drug, biocompatibility, biodegradability, and non-immunogenicity. In this review, the advanced functions of the chitosan-based hydrogels are summarized, with emphasis on fabrications and resultant properties reported in literature from the recent decade. The recent progress in the applications of drug delivery, tissue engineering, disease treatments, and biosensors are reviewed. Current challenges and future development direction of the chitosan-based hydrogels for pharmaceutical and biomedical applications are prospected.
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spelling pubmed-101383042023-04-28 Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications Taokaew, Siriporn Kaewkong, Worasak Kriangkrai, Worawut Gels Review Chitosan is a promising naturally derived polysaccharide to be used in hydrogel forms for pharmaceutical and biomedical applications. The multifunctional chitosan-based hydrogels have attractive properties such as the ability to encapsulate, carry, and release the drug, biocompatibility, biodegradability, and non-immunogenicity. In this review, the advanced functions of the chitosan-based hydrogels are summarized, with emphasis on fabrications and resultant properties reported in literature from the recent decade. The recent progress in the applications of drug delivery, tissue engineering, disease treatments, and biosensors are reviewed. Current challenges and future development direction of the chitosan-based hydrogels for pharmaceutical and biomedical applications are prospected. MDPI 2023-03-27 /pmc/articles/PMC10138304/ /pubmed/37102889 http://dx.doi.org/10.3390/gels9040277 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Taokaew, Siriporn
Kaewkong, Worasak
Kriangkrai, Worawut
Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications
title Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications
title_full Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications
title_fullStr Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications
title_full_unstemmed Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications
title_short Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications
title_sort recent development of functional chitosan-based hydrogels for pharmaceutical and biomedical applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138304/
https://www.ncbi.nlm.nih.gov/pubmed/37102889
http://dx.doi.org/10.3390/gels9040277
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