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Molecular and Pathological Analyses of IARS1-Deficient Mice: An IARS Disorder Model

Most mitochondrial diseases are hereditary and highly heterogeneous. Cattle born with the V79L mutation in the isoleucyl-tRNA synthetase 1 (IARS1) protein exhibit weak calf syndrome. Recent human genomic studies about pediatric mitochondrial diseases also identified mutations in the IARS1 gene. Alth...

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Detalles Bibliográficos
Autores principales:	Watanabe, Masaki, Shishido, Koya, Kanehira, Nao, Hiura, Koki, Nakano, Kenta, Okamura, Tadashi, Ando, Ryo, Sasaki, Hayato, Sasaki, Nobuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138339/ https://www.ncbi.nlm.nih.gov/pubmed/37108118 http://dx.doi.org/10.3390/ijms24086955

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