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Study of Lipophilicity and ADME Properties of 1,9-Diazaphenothiazines with Anticancer Action

Lipophilicity is one of the key properties of a potential drug that determines the solubility, the ability to penetrate through cell barriers, and transport to the molecular target. It affects pharmacokinetic processes such as adsorption, distribution, metabolism, excretion (ADME). The 10-substitute...

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Detalles Bibliográficos
Autores principales: Morak-Młodawska, Beata, Jeleń, Małgorzata, Martula, Emilia, Korlacki, Rafał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138389/
https://www.ncbi.nlm.nih.gov/pubmed/37108135
http://dx.doi.org/10.3390/ijms24086970