Cargando…
Study of Lipophilicity and ADME Properties of 1,9-Diazaphenothiazines with Anticancer Action
Lipophilicity is one of the key properties of a potential drug that determines the solubility, the ability to penetrate through cell barriers, and transport to the molecular target. It affects pharmacokinetic processes such as adsorption, distribution, metabolism, excretion (ADME). The 10-substitute...
Autores principales: | Morak-Młodawska, Beata, Jeleń, Małgorzata, Martula, Emilia, Korlacki, Rafał |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138389/ https://www.ncbi.nlm.nih.gov/pubmed/37108135 http://dx.doi.org/10.3390/ijms24086970 |
Ejemplares similares
-
Synthesis, Anticancer Activity, and Apoptosis Induction of Novel 3,6-Diazaphenothiazines †
por: Morak-Młodawska, Beata, et al.
Publicado: (2019) -
Synthesis, spectroscopic characterization, and anticancer activity of new 10-substituted 1,6-diazaphenothiazines
por: Morak-Młodawska, Beata, et al.
Publicado: (2016) -
Lipophilicity and Pharmacokinetic Properties of New Anticancer Dipyridothiazine with 1,2,3-Triazole Substituents
por: Morak-Młodawska, Beata, et al.
Publicado: (2022) -
Synthesis and selected immunological properties of 10-substituted 1,8-diazaphenothiazines
por: Morak-Młodawska, Beata, et al.
Publicado: (2014) -
10H-1,9-diazaphenothiazine and its 10-derivatives: synthesis, characterisation and biological evaluation as potential anticancer agents
por: Morak-Młodawska, Beata, et al.
Publicado: (2019)