The “Asthma-Polycystic Ovary Overlap Syndrome” and the Therapeutic Role of Myo-Inositol

Asthma is a heterogeneous inflammatory disease characterized by abnormalities in immune response. Due to the inherent complexity of the disease and the presence of comorbidities, asthma control is often difficult to obtain. In asthmatic patients, an increased prevalence of irregular menstrual cycles...

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Detalles Bibliográficos
Autores principales: Guarnieri, Gabriella, Iervolino, Matteo, Cavallone, Sara, Unfer, Vittorio, Vianello, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138395/
https://www.ncbi.nlm.nih.gov/pubmed/37108123
http://dx.doi.org/10.3390/ijms24086959
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author Guarnieri, Gabriella
Iervolino, Matteo
Cavallone, Sara
Unfer, Vittorio
Vianello, Andrea
author_facet Guarnieri, Gabriella
Iervolino, Matteo
Cavallone, Sara
Unfer, Vittorio
Vianello, Andrea
author_sort Guarnieri, Gabriella
collection PubMed
description Asthma is a heterogeneous inflammatory disease characterized by abnormalities in immune response. Due to the inherent complexity of the disease and the presence of comorbidities, asthma control is often difficult to obtain. In asthmatic patients, an increased prevalence of irregular menstrual cycles, infertility, obesity, and insulin resistance has been reported. Given that these conditions are also common in patients with polycystic ovary syndrome (PCOS), we propose the definition of “asthma-PCOS overlap syndrome” to indicate a medical condition which shares characteristics of both diseases. The aim of this review is to analyze the links between asthma and PCOS and evaluate the therapeutic role of myo-inositol, a natural compound currently utilized in patients with PCOS, in the management of asthma patients.
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spelling pubmed-101383952023-04-28 The “Asthma-Polycystic Ovary Overlap Syndrome” and the Therapeutic Role of Myo-Inositol Guarnieri, Gabriella Iervolino, Matteo Cavallone, Sara Unfer, Vittorio Vianello, Andrea Int J Mol Sci Review Asthma is a heterogeneous inflammatory disease characterized by abnormalities in immune response. Due to the inherent complexity of the disease and the presence of comorbidities, asthma control is often difficult to obtain. In asthmatic patients, an increased prevalence of irregular menstrual cycles, infertility, obesity, and insulin resistance has been reported. Given that these conditions are also common in patients with polycystic ovary syndrome (PCOS), we propose the definition of “asthma-PCOS overlap syndrome” to indicate a medical condition which shares characteristics of both diseases. The aim of this review is to analyze the links between asthma and PCOS and evaluate the therapeutic role of myo-inositol, a natural compound currently utilized in patients with PCOS, in the management of asthma patients. MDPI 2023-04-09 /pmc/articles/PMC10138395/ /pubmed/37108123 http://dx.doi.org/10.3390/ijms24086959 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Guarnieri, Gabriella
Iervolino, Matteo
Cavallone, Sara
Unfer, Vittorio
Vianello, Andrea
The “Asthma-Polycystic Ovary Overlap Syndrome” and the Therapeutic Role of Myo-Inositol
title The “Asthma-Polycystic Ovary Overlap Syndrome” and the Therapeutic Role of Myo-Inositol
title_full The “Asthma-Polycystic Ovary Overlap Syndrome” and the Therapeutic Role of Myo-Inositol
title_fullStr The “Asthma-Polycystic Ovary Overlap Syndrome” and the Therapeutic Role of Myo-Inositol
title_full_unstemmed The “Asthma-Polycystic Ovary Overlap Syndrome” and the Therapeutic Role of Myo-Inositol
title_short The “Asthma-Polycystic Ovary Overlap Syndrome” and the Therapeutic Role of Myo-Inositol
title_sort “asthma-polycystic ovary overlap syndrome” and the therapeutic role of myo-inositol
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138395/
https://www.ncbi.nlm.nih.gov/pubmed/37108123
http://dx.doi.org/10.3390/ijms24086959
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