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Diplacone Isolated from Paulownia tomentosa Mature Fruit Induces Ferroptosis-Mediated Cell Death through Mitochondrial Ca(2+) Influx and Mitochondrial Permeability Transition

The recently defined type of cell death ferroptosis has garnered significant attention as a potential new approach to cancer treatment owing to its more immunogenic nature when compared with apoptosis. Ferroptosis is characterized by the depletion of glutathione (GSH)/glutathione peroxidase-4 (GPx4)...

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Detalles Bibliográficos
Autores principales: Kang, Myung-Ji, Ryu, Hyung Won, Oh, Eun Sol, Song, Yu Na, Huh, Yang Hoon, Park, Ji-Yoon, Oh, Seon Min, Lee, Su-Yeon, Park, Yhun Jung, Kim, Doo-Young, Ro, Hyunju, Hong, Sung-Tae, Lee, Su Ui, Moon, Dong-Oh, Kim, Mun-Ock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138418/
https://www.ncbi.nlm.nih.gov/pubmed/37108220
http://dx.doi.org/10.3390/ijms24087057