HP1γ Prevents Activation of the cGAS/STING Pathway by Preserving Nuclear Envelope and Genomic Integrity in Colon Adenocarcinoma Cells

Chronic inflammatory processes in the intestine result in serious conditions such as inflammatory bowel disease (IBD) and cancer. An increased detection of cytoplasmic DNA sensors has been reported in the IBD colon mucosa, suggesting their contribution in mucosal inflammation. Yet, the mechanisms al...

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Detalles Bibliográficos
Autores principales: Mata-Garrido, Jorge, Frizzi, Laura, Nguyen, Thien, He, Xiangyan, Chang-Marchand, Yunhua, Xiang, Yao, Reisacher, Caroline, Casafont, Iñigo, Arbibe, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138453/
https://www.ncbi.nlm.nih.gov/pubmed/37108510
http://dx.doi.org/10.3390/ijms24087347

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