Cargando…

Design, Synthesis and Cytotoxic Activity of Novel Salicylaldehyde Hydrazones against Leukemia and Breast Cancer

Despite the significant advancements in complex anticancer therapy, the search for new and more efficient specific anticancer agents remains a top priority in the field of drug discovery and development. Here, based on the structure-activity relationships (SARs) of eleven salicylaldehyde hydrazones...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nikolova-Mladenova, Boryana, Momekov, Georgi, Zhivkova, Zvetanka, Doytchinova, Irini
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138506/ https://www.ncbi.nlm.nih.gov/pubmed/37108514 http://dx.doi.org/10.3390/ijms24087352

Ejemplares similares

Gallium (III) Complexes with 5-Bromosalicylaldehyde Benzoylhydrazones: In Silico Studies and In Vitro Cytotoxic Activity
por: Nikolova-Mladenova, Boryana, et al.
Publicado: (2022)

Novel Arylsulfonylhydrazones as Breast Anticancer Agents Discovered by Quantitative Structure-Activity Relationships
por: Angelova, Violina T., et al.
Publicado: (2023)

Novel hits for acetylcholinesterase inhibition derived by docking-based screening on ZINC database
por: Doytchinova, Irini, et al.
Publicado: (2018)

4-(Diethylamino)salicylaldehyde phenylsulfonylhydrazone
por: Tai, Xi-Shi, et al.
Publicado: (2008)

Effect of a Substituent on the Properties of Salicylaldehyde Hydrazone Derivatives
por: Hoelm, Marta, et al.
Publicado: (2023)

Galantamine-Curcumin Hybrids as Dual-Site Binding Acetylcholinesterase Inhibitors
por: Stavrakov, Georgi, et al.
Publicado: (2020)

Analgesic and Anti-Inflammatory Activities of Salicylaldehyde 2-Chlorobenzoyl Hydrazone (H(2)LASSBio-466), Salicylaldehyde 4-Chlorobenzoyl Hydrazone (H(2)LASSBio-1064) and Their Zinc(II) Complexes
por: Júnior, Walfrido Bispo, et al.
Publicado: (2011)

Structure-Activity Relationships of Novel Salicylaldehyde Isonicotinoyl Hydrazone (SIH) Analogs: Iron Chelation, Anti-Oxidant and Cytotoxic Properties
por: Potůčková, Eliška, et al.
Publicado: (2014)

A Galantamine–Curcumin Hybrid Decreases the Cytotoxicity of Amyloid-Beta Peptide on SH-SY5Y Cells
por: Mladenova, Kirilka, et al.
Publicado: (2021)

Sulfadiazine Salicylaldehyde-Based Schiff Bases: Synthesis, Antimicrobial Activity and Cytotoxicity
por: Krátký, Martin, et al.
Publicado: (2017)

A salicylaldehyde benzoyl hydrazone based near-infrared probe for copper(ii) and its bioimaging applications
por: Zhao, Jie, et al.
Publicado: (2022)

Modulation Effect on Tubulin Polymerization, Cytotoxicity and Antioxidant Activity of 1H-Benzimidazole-2-Yl Hydrazones
por: Argirova, Maria, et al.
Publicado: (2022)

Crystal Violet Lactone Salicylaldehyde Hydrazone Zn(II) Complex: a Reversible Photochromic Material both in Solution and in Solid Matrix
por: Li, Kai, et al.
Publicado: (2015)

Synthesis, Characterization, and Cytotoxic Activity of New Lanthanum(III) Complexes of Bis-Coumarins
por: Kostova, Irena, et al.
Publicado: (2006)

Drug Design—Past, Present, Future
por: Doytchinova, Irini
Publicado: (2022)

Synthesis of 2H-Chromenones from Salicylaldehydes and Arylacetonitriles
por: Li, Chengcai, et al.
Publicado: (2017)

Charge-transport properties of 4-(1,2,2-triphenylvinyl)aniline salicylaldehyde hydrazone: tight-packing induced molecular ‘hardening’
por: Ma, Huipeng, et al.
Publicado: (2017)

Synthesis, Antiplatelet Activity and Cytotoxicity Assessment of Indole-Based Hydrazone Derivatives
por: Haj Mohammad Ebrahim Tehrani, Kamaleddin, et al.
Publicado: (2015)

3,5-Dichlorosalicylaldehyde
por: Azizul, Isha, et al.
Publicado: (2008)

T-cell epitope vaccine design by immunoinformatics
por: Patronov, Atanas, et al.
Publicado: (2013)

Design, Synthesis, and Anticancer Evaluation of Novel Tetracaine Hydrazide-Hydrazones
por: Han, M. İhsan, et al.
Publicado: (2023)

(Z)-Selective Takai olefination of salicylaldehydes
por: Geddis, Stephen M, et al.
Publicado: (2017)

Catalytic asymmetric hydrometallation of cyclobutenes with salicylaldehydes
por: Goetzke, F. Wieland, et al.
Publicado: (2021)

Synthesis and Cytotoxic Activity of New Thiazolopyrimidine Sugar Hydrazones and Their Derived Acyclic Nucleoside Analogues
por: Basiony, Ebtesam A., et al.
Publicado: (2020)

Synthesis and Characterization of Novel Hydrazone Derivatives of Isonicotinic Hydrazide and Their Evaluation for Antibacterial and Cytotoxic Potential
por: Shah, Muhammad Abdullah, et al.
Publicado: (2022)

New p-Substituted Salicylaldehyde Phenylhydrazone Derivatives: Synthesis, Characterization, and Antioxidant Activities
por: Yorur-Goreci, Cigdem, et al.
Publicado: (2014)

Palladium(II) Complexes of Substituted Salicylaldehydes: Synthesis, Characterization and Investigation of Their Biological Profile
por: Zianna, Ariadni, et al.
Publicado: (2022)

4-(Diethylamino)salicylaldehyde azine
por: Qiu, Jing-Bo, et al.
Publicado: (2011)

Correction: Catalytic asymmetric hydrometallation of cyclobutenes with salicylaldehydes
por: Goetzke, F. Wieland, et al.
Publicado: (2022)

Recent advances in the synthesis of fluorinated hydrazones
por: Guo, Rui, et al.
Publicado: (2018)

A Novel Galantamine-Curcumin Hybrid as a Potential Multi-Target Agent against Neurodegenerative Disorders
por: Simeonova, Rumyana, et al.
Publicado: (2021)

Novel synthesis of oxoacetamides via reaction of salicylaldehyde and isocyanide under mild reaction condition
por: Bayat, Mohammad, et al.
Publicado: (2020)

An Efficient Synthesis, Spectroscopic Characterization, and Optical Nonlinearity Response of Novel Salicylaldehyde Thiosemicarbazone Derivatives
por: Khalid, Muhammad, et al.
Publicado: (2021)

ROS-Mediated Cytotoxic Effect of Copper(II) Hydrazone Complexes against Human Glioma Cells
por: Despaigne, Angel A. Recio, et al.
Publicado: (2014)

Discovery of a Novel Acetylcholinesterase Inhibitor by Fragment-Based Design and Virtual Screening
por: Stavrakov, Georgi, et al.
Publicado: (2021)

Resveratrol/Hydrazone Hybrids: Synthesis and Chemopreventive Activity against Colorectal Cancer Cells
por: Castrillón-López, Wilson, et al.
Publicado: (2022)

Synthesis and redetermination of the crystal structure of salicylaldehyde N(4)-morpholinothiosemicarbazone
por: Tran Buu, Dang, et al.
Publicado: (2019)

Benzyl Alcohol/Salicylaldehyde-Type Polyketide Metabolites of Fungi: Sources, Biosynthesis, Biological Activities, and Synthesis
por: Štiblariková, Mária, et al.
Publicado: (2022)

Ex Vivo Antioxidant and Cholinesterase Inhibiting Effects of a Novel Galantamine–Curcumin Hybrid on Scopolamine-Induced Neurotoxicity in Mice
por: Simeonova, Rumyana, et al.
Publicado: (2022)

Novel Pyrazole-Hydrazone Derivatives Containing an Isoxazole Moiety: Design, Synthesis, and Antiviral Activity
por: Yang, Zaibo, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5jo871orp9d08af6c68qdb3bo7