Cargando…

R-Loops and R-Loop-Binding Proteins in Cancer Progression and Drug Resistance

R-loops are three-stranded DNA/RNA hybrids that form by the annealing of the mRNA transcript to its coding template while displacing the non-coding strand. While R-loop formation regulates physiological genomic and mitochondrial transcription and DNA damage response, imbalanced R-loop formation can...

Descripción completa

Detalles Bibliográficos
Autores principales:	Elsakrmy, Noha, Cui, Haissi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138518/ https://www.ncbi.nlm.nih.gov/pubmed/37108225 http://dx.doi.org/10.3390/ijms24087064

Ejemplares similares

R-loopDB: a database for R-loop forming sequences (RLFS) and R-loops
por: Jenjaroenpun, Piroon, et al.
Publicado: (2017)

R-Loops in Genome Instability and Cancer
por: Li, Fang, et al.
Publicado: (2023)

Integrative analysis and prediction of human R-loop binding proteins
por: Kumar, Arun, et al.
Publicado: (2022)

The mitochondrial R-loop
por: Holt, Ian J
Publicado: (2019)

Helicases in R-loop Formation and Resolution
por: Yang, Shizhuo, et al.
Publicado: (2023)

R-loopBase: a knowledgebase for genome-wide R-loop formation and regulation
por: Lin, Ruoyao, et al.
Publicado: (2021)

Out of Balance: R-loops in Human Disease
por: Groh, Matthias, et al.
Publicado: (2014)

R Loops in the Regulation of Antibody Gene Diversification
por: Pavri, Rushad
Publicado: (2017)

The makings of TERRA R-loops at chromosome ends
por: Fernandes, Rita Valador, et al.
Publicado: (2021)

The Association of R-Loop Binding Proteins Subtypes with CIN Implicates Therapeutic Strategies in Colorectal Cancer
por: Zhao, Wenchao, et al.
Publicado: (2022)

Pathophysiological Role and Diagnostic Potential of R-Loops in Cancer and Beyond
por: Khan, Essak S., et al.
Publicado: (2022)

R-loops in neuronal aging
por: Hall, Hana
Publicado: (2023)

Quality-controlled R-loop meta-analysis reveals the characteristics of R-loop consensus regions
por: Miller, Henry E, et al.
Publicado: (2022)

The intrinsic ability of double-stranded DNA to carry out D-loop and R-loop formation
por: Shibata, Takehiko, et al.
Publicado: (2020)

Clinical and Mechanistic Implications of R-Loops in Human Leukemias
por: Lee, Seo-Yun, et al.
Publicado: (2023)

The Role of Replication-Associated Repair Factors on R-Loops
por: Bhatia, Vaibhav, et al.
Publicado: (2017)

R-loops: formation, function, and relevance to cell stress
por: Allison, David F, et al.
Publicado: (2019)

R-loop induced G-quadruplex in non-template promotes transcription by successive R-loop formation
por: Lee, Chun-Ying, et al.
Publicado: (2020)

R-loop Mapping and Characterization During Drosophila Embryogenesis Reveals Developmental Plasticity in R-loop Signatures
por: Munden, Alexander, et al.
Publicado: (2022)

Senataxin and R-loops homeostasis: multifaced implications in carcinogenesis
por: Gatti, Veronica, et al.
Publicado: (2023)

R-loops highlight the nucleus in ALS
por: Salvi, Jayesh S, et al.
Publicado: (2015)

TonEBP recognizes R-loops and initiates m6A RNA methylation for R-loop resolution
por: Kang, Hyun Je, et al.
Publicado: (2020)

R-Loop Tracker: Web Access-Based Tool for R-Loop Detection and Analysis in Genomic DNA Sequences
por: Brázda, Václav, et al.
Publicado: (2021)

Strengths and Weaknesses of the Current Strategies to Map and Characterize R-Loops
por: Vanoosthuyse, Vincent
Publicado: (2018)

A Tale of Loops and Tails: The Role of Intrinsically Disordered Protein Regions in R-Loop Recognition and Phase Separation
por: Dettori, Leonardo G., et al.
Publicado: (2021)

TDP-43 mutations link Amyotrophic Lateral Sclerosis with R-loop homeostasis and R loop-mediated DNA damage
por: Giannini, Marta, et al.
Publicado: (2020)

The integrated stress response induces R-loops and hinders replication fork progression
por: Choo, Josephine Ann Mun Yee, et al.
Publicado: (2020)

R-Loop Formation In Trans at an AGGAG Repeat
por: Toriumi, Kazuya, et al.
Publicado: (2013)

R-loops in bacterial transcription: Their causes and consequences
por: Gowrishankar, J, et al.
Publicado: (2013)

R-loops modulate Trypanosome antigenic variation
por: Prister, Lauren L., et al.
Publicado: (2018)

Replisome bypass of transcription complexes and R-loops
por: Brüning, Jan-Gert, et al.
Publicado: (2020)

Two-loop electroweak contributions to $\Delta r$
por: Freitas, A., et al.
Publicado: (2001)

R-Loops at Chromosome Ends: From Formation, Regulation, and Cellular Consequence
por: Gong, Yi, et al.
Publicado: (2023)

Replication Fork Protection Factors Controlling R-Loop Bypass and Suppression
por: Chang, Emily Yun-Chia, et al.
Publicado: (2017)

R-Loop-Associated Genomic Instability and Implication of WRN and WRNIP1
por: Marabitti, Veronica, et al.
Publicado: (2022)

Identification of critical residues in loop E in the 5-HT(3AS)R binding site
por: Venkataraman, Padmavati, et al.
Publicado: (2002)

On the R and R$_{\tau}$ ratios at the five-loop level of perturbative QCD
por: Samuel, Mark A
Publicado: (1993)

The miR155HG/miR-185/ANXA2 loop contributes to glioblastoma growth and progression
por: Wu, Weining, et al.
Publicado: (2019)

NUSAP1 Binds ILF2 to Modulate R-Loop Accumulation and DNA Damage in Prostate Cancer
por: Chiu, Chun-Lung, et al.
Publicado: (2023)

Correction: The integrated stress response induces R-loops and hinders replication fork progression
por: Choo, Josephine Ann Mun Yee, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fpk6a2oo7qtrqrup37gq9j9ug5