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Characterization of a convection‐based support microstructure through a flow resistance parameter

Modern convection‐based supports differ substantially in pore size, porosity, and microstructure topology. Due to such variability, it is challenging to evaluate the contribution of a particular microstructure topology on flow resistance. We demonstrated that the flow resistance parameter ([Formula:...

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Autor principal: Podgornik, Aleš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138761/
https://www.ncbi.nlm.nih.gov/pubmed/35218615
http://dx.doi.org/10.1002/jssc.202100955
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author Podgornik, Aleš
author_facet Podgornik, Aleš
author_sort Podgornik, Aleš
collection PubMed
description Modern convection‐based supports differ substantially in pore size, porosity, and microstructure topology. Due to such variability, it is challenging to evaluate the contribution of a particular microstructure topology on flow resistance. We demonstrated that the flow resistance parameter ([Formula: see text]) introduced decades ago can be used as a criterion to evaluate the effect of microstructure topology on a pressure drop when the pore size is used as a characteristic support dimension. Furthermore, the [Formula: see text] value of simple cubic packing was calculated over the entire range of open porosity and compared to the [Formula: see text] values determined for pressure drop models derived for particular convection‐based supports and experimental values of various convection‐based supports from the literature. It was shown that different convection‐based supports become clustered into distinct groups when plotted according to their [Formula: see text] and open porosity values, allowing their discrimination.
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spelling pubmed-101387612023-04-28 Characterization of a convection‐based support microstructure through a flow resistance parameter Podgornik, Aleš J Sep Sci Liquid Chromatography Modern convection‐based supports differ substantially in pore size, porosity, and microstructure topology. Due to such variability, it is challenging to evaluate the contribution of a particular microstructure topology on flow resistance. We demonstrated that the flow resistance parameter ([Formula: see text]) introduced decades ago can be used as a criterion to evaluate the effect of microstructure topology on a pressure drop when the pore size is used as a characteristic support dimension. Furthermore, the [Formula: see text] value of simple cubic packing was calculated over the entire range of open porosity and compared to the [Formula: see text] values determined for pressure drop models derived for particular convection‐based supports and experimental values of various convection‐based supports from the literature. It was shown that different convection‐based supports become clustered into distinct groups when plotted according to their [Formula: see text] and open porosity values, allowing their discrimination. John Wiley and Sons Inc. 2022-03-07 2022-06 /pmc/articles/PMC10138761/ /pubmed/35218615 http://dx.doi.org/10.1002/jssc.202100955 Text en © 2022 The Authors. Journal of Separation Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Liquid Chromatography
Podgornik, Aleš
Characterization of a convection‐based support microstructure through a flow resistance parameter
title Characterization of a convection‐based support microstructure through a flow resistance parameter
title_full Characterization of a convection‐based support microstructure through a flow resistance parameter
title_fullStr Characterization of a convection‐based support microstructure through a flow resistance parameter
title_full_unstemmed Characterization of a convection‐based support microstructure through a flow resistance parameter
title_short Characterization of a convection‐based support microstructure through a flow resistance parameter
title_sort characterization of a convection‐based support microstructure through a flow resistance parameter
topic Liquid Chromatography
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138761/
https://www.ncbi.nlm.nih.gov/pubmed/35218615
http://dx.doi.org/10.1002/jssc.202100955
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