Rapid and Robust Multi-Phenotypic Assay System for ALS Using Human iPS Cells with Mutations in Causative Genes

Amyotrophic lateral sclerosis (ALS) is a major life-threatening disease caused by motor neuron degeneration. More effective treatments through drug discovery are urgently needed. Here, we established an effective high-throughput screening system using induced pluripotent stem cells (iPSCs). Using a...

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Detalles Bibliográficos
Autores principales: Kondo, Tosho, Ebinuma, Ihori, Tanaka, Hirotaka, Nishikawa, Yukitoshi, Komiya, Takaki, Ishikawa, Mitsuru, Okano, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138792/
https://www.ncbi.nlm.nih.gov/pubmed/37108151
http://dx.doi.org/10.3390/ijms24086987

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