Redox and Nucleophilic Reactions of Naphthoquinones with Small Thiols and Their Effects on Oxidization of H(2)S to Inorganic and Organic Hydropolysulfides and Thiosulfate

Naphthoquinone (1,4-NQ) and its derivatives (NQs, juglone, plumbagin, 2-methoxy-1,4-NQ, and menadione) have a variety of therapeutic applications, many of which are attributed to redox cycling and the production of reactive oxygen species (ROS). We previously demonstrated that NQs also oxidize hydro...

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Detalles Bibliográficos
Autores principales: Olson, Kenneth R., Clear, Kasey J., Gao, Yan, Ma, Zhilin, Cieplik, Nathaniel M., Fiume, Alyssa R., Gaziano, Dominic J., Kasko, Stephen M., Luu, Jennifer, Pfaff, Ella, Travlos, Anthony, Velander, Cecilia, Wilson, Katherine J., Edwards, Elizabeth D., Straub, Karl D., Wu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138938/
https://www.ncbi.nlm.nih.gov/pubmed/37108682
http://dx.doi.org/10.3390/ijms24087516

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