Inhibition of GSK-3β Enhances Osteoblast Differentiation of Human Mesenchymal Stem Cells through Wnt Signalling Overexpressing Runx2

Small-molecule-inhibitor-based bone differentiation has been recently exploited as a novel approach to regulating osteogenesis-related signaling pathways. In this study, we identified 1-Azakenpaullone, a highly selective inhibitor of glycogen synthase kinase-3β (GSK-3β), as a powerful inducer of ost...

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Detalles Bibliográficos
Autores principales: AlMuraikhi, Nihal, Binhamdan, Sarah, Alaskar, Hanouf, Alotaibi, Amal, Tareen, Sumaiya, Muthurangan, Manikandan, Alfayez, Musaad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139012/
https://www.ncbi.nlm.nih.gov/pubmed/37108323
http://dx.doi.org/10.3390/ijms24087164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139012/
https://www.ncbi.nlm.nih.gov/pubmed/37108323
http://dx.doi.org/10.3390/ijms24087164

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