Cargando…
Immunopathological Alterations after Blast Injury and Hemorrhage in a Swine Model of Prolonged Damage Control Resuscitation
Trauma-related hemorrhagic shock (HS) remains a leading cause of death among military and civilian trauma patients. We have previously shown that administration of complement and HMGB1 inhibitors attenuate morbidity and mortality 24 h after injury in a rat model of blast injury (BI) and HS. To furth...
Autores principales: | Simovic, Milomir O., Yang, Zhangsheng, Jordan, Bryan S., Fraker, Tamara L., Cancio, Tomas S., Lucas, Michael L., Cancio, Leopoldo C., Li, Yansong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139120/ https://www.ncbi.nlm.nih.gov/pubmed/37108656 http://dx.doi.org/10.3390/ijms24087494 |
Ejemplares similares
-
Complement inhibition ameliorates blast-induced acute lung injury in rats: Potential role of complement in intracellular HMGB1-mediated inflammation
por: Li, Yansong, et al.
Publicado: (2018) -
HMGB1 Inhibition to Ameliorate Organ Failure and Increase Survival in Trauma
por: Yang, Zhangsheng, et al.
Publicado: (2022) -
Traumatized triad of complementopathy, endotheliopathy, and coagulopathy ˗ Impact on clinical outcomes in severe polytrauma patients
por: Yang, Zhangsheng, et al.
Publicado: (2022) -
Immunopathology of terminal complement activation and complement C5 blockade creating a pro‐survival and organ‐protective phenotype in trauma
por: Yang, Zhangsheng, et al.
Publicado: (2022) -
Distal organ inflammation and injury after resuscitative endovascular balloon occlusion of the aorta in a porcine model of severe hemorrhagic shock
por: Li, Yansong, et al.
Publicado: (2020)