Methylation and silencing of the retinoic acid receptor-β2 gene in cervical cancer

BACKGROUND: Expression of the retinoic acid receptor β2 (RAR-β2), a putative tumor suppressor gene, is reduced in various human cancers, including squamous cell carcinomas (SCC) of the uterine cervix. The mechanism of the inhibition of RAR-β2 expression remains obscure. We examined whether methylati...

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Detalles Bibliográficos
Autores principales: Ivanova, Tatyana, Petrenko, Anatolii, Gritsko, Tatyana, Vinokourova, Svetlana, Eshilev, Ernest, Kobzeva, Vera, Kisseljov, Fjodor, Kisseljova, Natalia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC101392/
https://www.ncbi.nlm.nih.gov/pubmed/11945179
http://dx.doi.org/10.1186/1471-2407-2-4

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