An Efficient 2D Protocol for Differentiation of iPSCs into Mature Postmitotic Dopaminergic Neurons: Application for Modeling Parkinson’s Disease

About 15% of patients with parkinsonism have a hereditary form of Parkinson’s disease (PD). Studies on the early stages of PD pathogenesis are challenging due to the lack of relevant models. The most promising ones are models based on dopaminergic neurons (DAns) differentiated from induced pluripote...

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Detalles Bibliográficos
Autores principales: Lebedeva, Olga S., Sharova, Elena I., Grekhnev, Dmitriy A., Skorodumova, Liubov O., Kopylova, Irina V., Vassina, Ekaterina M., Oshkolova, Arina, Novikova, Iuliia V., Krisanova, Alena V., Olekhnovich, Evgenii I., Vigont, Vladimir A., Kaznacheyeva, Elena V., Bogomazova, Alexandra N., Lagarkova, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139404/
https://www.ncbi.nlm.nih.gov/pubmed/37108456
http://dx.doi.org/10.3390/ijms24087297

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